These would otherwise not be possible to do using the in-game settings. The switches -noprefetch and -noshadows used above prevent prefetching of data and also disable all non-Sun shadows in the game engine.
Clear Sky\bin\xrEngine.exe' -noprefetch -noshadows 'C:\Program Files\Deep Silver\S.T.A.L.K.E.R. Then in the Target box, one space after the last character, insert the switch(es) you wish to use, each separated by one blank space. To use a command line switch, go to your STALKER: Clear Sky launch icon, right-click on it and select Properties.
These 'switches' are commands which are passed on to the game's main executable file xrEngine.exe, telling the engine to do certain things as the game launches. There are a range of additional commands you can execute when first launching Clear Sky called Command Line Switches.
STALKER: Clear Sky Tweak Guide Advanced Tweaking (Pt.3)